Applicants to this grant opportunity must propose a Phase III clinical trial in Australia in collaboration with international counterparts. Where applicants are proposing to lead an international collaborative clinical trial, MRFF funding is available to support overarching coordination of trial sites both in Australia and overseas and to operate one or more clinical trial sites in Australia. Alternatively, where applicants are proposing to contribute to clinical trials initiated by the international partners, MRFF funding is available to coordinate Australian involvement and to conduct one or more clinical trial sites in Australia. The clinical trial should not have commenced recruitment at the Australian trial site/s. Please note the 2026 MRFF International Clinical Trial Collaborations grant opportunity will be open for one round only.