NITRO clinical trial information
Dataset Name: A Phase III, randomised trial of adding nitroglycerin to first line chemotherapy for advanced non-small cell lung cancer
Author: Prof Andrew Davidson, Royal Perth Hospital
Publisher: Thoracic Oncology Group Australasia
Funding: Cancer Council WA, Cancer Council QLD, Cancer Council NSW, National Health and Medical Research Council.
DOI: 10.58106/914n-jz74
Date made available: 2023
Subject: Chemotherapy
Dataset: Individual participant data
Patient sample size: 372
Dataset description: Data for 372 adult patients with advanced non-small cell lung cancer. Treatment regime was standard chemotherapy with (n=185) or without (n=187) application of a nitroglycerin 25 mg patch. Study assessments were carried out at baseline before randomization, then every 3 weeks during chemotherapy, and every 4 weeks from completion of chemotherapy until disease progression. Dataset includes: Progression free survival, overall survival data, demographic data, diagnostic data, treatment data, quality of life data, objective tumour response. (RECIST 1.1), adverse events.
Requests for Data: Access can be requested via the Health Data Australia catalogue. Search for the ACTRN number in the catalogue to find datasets associated with this trial or email enquiries to info@thoraciconcology.org.au
